BDBM60500 US9079913, MI-519-10-me

SMILES CN1[C@H](CC(C)(C)C)[C@@]2([C@H]([C@@H]1C(=O)NCC[C@@H](O)CO)c1cccc(Cl)c1F)C(=O)Nc1cc(F)c(F)cc21

InChI Key InChIKey=NCVZNOICJNGHGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60500   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM60500(US9079913, MI-519-10-me)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
US Patent