BDBM60535 US9102591, (+)2-chloro-N-[2-(4,4-difluorocyclohexyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethyl]-6-fluoro-benzamide

SMILES Fc1cccc(Cl)c1C(=O)NC[C@@H](C1CCC(F)(F)CC1)c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=BBABFHCUJHALBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60535   

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM60535(US9102591, (+)2-chloro-N-[2-(4,4-difluorocyclohexy...)
Affinity DataIC50: 75nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent