BDBM6097 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[(1-methylpiperidin-4-yl)oxy]quinoline-3-carbonitrile::4-phenylamino-3-quinolinecarbonitrile 8

SMILES COc1cc(Nc2c(cnc3cc(OC4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=SRTONYAWGLMSSN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6097   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  230nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  89nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  89nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed