BDBM6190 3-tert-butyl-1-(2-{[4-(diethylamino)butyl]amino}-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea::CHEMBL189584::N-(tert-Butyl)-N -[2-[[4-(diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea::Pyrido[2,3-d]pyrimidine 12

SMILES: CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1

InChI Key: InChIKey=DXCUKNQANPLTEJ-UHFFFAOYSA-N

Data: 20 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 6190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 2 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 3 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Serine-protein kinase ATM (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Mouse)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Mouse)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6190 (CHEMBL189584 | 3-tert-butyl-1-(2-{[4-(diethylamino...) Show SMILES Show InChI	GoogleScholar	UniChem		45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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