BDBM6219 BMCL182776 Compound 1::Chlorobenzodioxole deriv. 28::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-amine

SMILES: COc1cc2c(cc1OCCCN3CCCCC3)ncnc2Nc4c(ccc5c4OCO5)Cl

InChI Key: InChIKey=QHIMVPIOWKYPSO-UHFFFAOYSA-N

Data: 7 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 6219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM6219 (BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM6219 (BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	25
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Vascular endothelial growth factor receptor 1 (Human)	BDBM6219 (BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM6219 (BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 4 (Human)	BDBM6219 (BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	7.4	22
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					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM6219 (BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM6219 (BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair