BDBM622107 US20230312550, Example 109::US20230312550, Example 67

SMILES: O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCOCC1)N1CSC[C@H]1C#N

InChI Key: InChIKey=GECJKRWOVGXGCO-UHFFFAOYSA-N

Data: 8 IC50  2 Kd  2 K_off  2 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 622107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	4.90E+6	n/a	n/a
TBA									Citation and Details
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Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0000460	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.20E+6	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00990	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0840	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0120	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a
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Presequence protease, mitochondrial (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Presequence protease, mitochondrial (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 2 (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 8 (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 9 (Human)	BDBM622107 (US20230312550, Example 109 | US20230312550, Exampl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair