BDBM622999 US11780845, Example 14

SMILES COc1cc(ccc1NC(=O)C=C)-c1c(-c2ccc(Oc3cccc(C)n3)cc2)c2c(N)ncnc2n1C

InChI Key InChIKey=QTXMAAOSUJWUBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622999   

TargetFibroblast growth factor receptor 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM622999(US11780845, Example 14)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were also tested in a FGFR2 Biochemical Caliper Assay. Compounds were prepared in 10 mM DMSO solution and serially...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent