BDBM625133 US20230322747, Compound 165

SMILES FC(F)c1nnc(o1)-c1cnc(COc2ccc(cc2)C#N)c(F)c1

InChI Key InChIKey=ZHLXGXRNTCKGNN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625133   

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandPNGBDBM625133(US20230322747, Compound 165)
Affinity DataIC50: 50nMAssay Description:The biochemical HDAC6 assay was performed using fluorescence detection (Fluor-De-Lys assay). In this assay, deacetylation of the Lysine residue in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent