BDBM625153 US20230322747, Compound 199

SMILES Cc1c[nH]c(n1)-c1cc(OCc2ccc(cn2)-c2nnc(o2)C(F)F)ccn1

InChI Key InChIKey=HRUAWEQNUGNNJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625153   

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandPNGBDBM625153(US20230322747, Compound 199)
Affinity DataIC50: 50nMAssay Description:The biochemical HDAC6 assay was performed using fluorescence detection (Fluor-De-Lys assay). In this assay, deacetylation of the Lysine residue in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent