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BDBM62676 MLS000085258::N-(3-methoxyphenyl)-3-[(5-phenyl-3-thiazolo[2,3-c][1,2,4]triazolyl)thio]propanamide::N-(3-methoxyphenyl)-3-[(5-phenyl-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)sulfanyl]propanamide::N-(3-methoxyphenyl)-3-[(5-phenyl[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)thio]propanamide::N-(3-methoxyphenyl)-3-[(5-phenylthiazolo[2,3-c][1,2,4]triazol-3-yl)thio]propionamide::SMR000019996::cid_1281415

SMILES: COc1cccc(NC(=O)CCSc2nnc3scc(-c4ccccc4)n23)c1

InChI Key: InChIKey=ZMXRWOAREBGSHJ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 62676   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hsf1 protein


(Mus musculus)
BDBM62676
PNG
(MLS000085258 | N-(3-methoxyphenyl)-3-[(5-phenyl-3-...)
Show SMILES COc1cccc(NC(=O)CCSc2nnc3scc(-c4ccccc4)n23)c1
Show InChI InChI=1S/C20H18N4O2S2/c1-26-16-9-5-8-15(12-16)21-18(25)10-11-27-19-22-23-20-24(19)17(13-28-20)14-6-3-2-4-7-14/h2-9,12-13H,10-11H2,1H3,(H,21,25)
PDB

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Similars

PCBioAssay
n/an/an/an/a>1.95E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MW2FKX
More data for this
Ligand-Target Pair