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BDBM63968 1-amino-3-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]urea::1-amino-3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]urea::1-amino-3-[4-[4-(4-methoxyphenyl)piperazino]phenyl]urea::1-azanyl-3-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]urea::MLS001181013::N-{4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl}hydrazinecarboxamide::SMR000477786::cid_820816

SMILES: COc1ccc(cc1)N1CCN(CC1)c1ccc(NC(=O)NN)cc1

InChI Key: InChIKey=SJJKOFVYSSHYQQ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63968   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hsf1 protein


(Mus musculus)
BDBM63968
PNG
(1-amino-3-[4-[4-(4-methoxyphenyl)-1-piperazinyl]ph...)
Show SMILES COc1ccc(cc1)N1CCN(CC1)c1ccc(NC(=O)NN)cc1
Show InChI InChI=1S/C18H23N5O2/c1-25-17-8-6-16(7-9-17)23-12-10-22(11-13-23)15-4-2-14(3-5-15)20-18(24)21-19/h2-9H,10-13,19H2,1H3,(H2,20,21,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>1.95E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MW2FKX
More data for this
Ligand-Target Pair