BDBM64540 4-[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]benzofuro[3,2-d]pyrimidine::4-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]-[1]benzofuro[3,2-d]pyrimidine::4-[4-[(E)-cinnamyl]piperazino]benzofuro[3,2-d]pyrimidine::MLS000041560::SMR000044666::cid_2012115

SMILES C(\C=C\c1ccccc1)N1CCN(CC1)c1ncnc2c3ccccc3oc12

InChI Key InChIKey=IUDWSLXQPWPEIJ-RMKNXTFCSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 64540   

TargetATP-dependent molecular chaperone HSP82(Candida albicans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64540(4-[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]benzo...)
Affinity DataEC50: >1.60E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, stress response Primary Collaborators: Susan Lindquist, Whitehead Insti...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Candida albicans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64540(4-[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]benzo...)
Affinity DataEC50: <120nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Candida albicans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64540(4-[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]benzo...)
Affinity DataEC50: >1.60E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein phosphatase(Candida dubliniensis CD36)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64540(4-[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]benzo...)
Affinity DataEC50:  1.80E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay