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BDBM64710 US8486940, 83

SMILES: Fc1cccc(c1)[C@H]1COC(=O)N1c1ccc2[nH]cnc2c1

InChI Key: InChIKey=ZPMHBHUZAKYRBJ-GGYSOQFKNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 64710   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM64710
PNG
(US8486940, 83)
Show SMILES Fc1cccc(c1)[C@H]1COC(=O)N1c1ccc2[nH]cnc2c1
Show InChI InChI=1/C16H12FN3O2/c17-11-3-1-2-10(6-11)15-8-22-16(21)20(15)12-4-5-13-14(7-12)19-9-18-13/h1-7,9,15H,8H2,(H,18,19)/t15-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a<1.00E+4n/an/an/an/an/an/a



Probiodrug AG

US Patent


Assay Description
Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...


US Patent US8486940 (2013)


BindingDB Entry DOI: 10.7270/Q2251GSF
More data for this
Ligand-Target Pair