BDBM64987 5-nitro-8-quinolinol::5-nitroquinolin-8-ol::8-HYDROXY-5-NITROQUINOLINE::MLS000069750::SMR000059036::cid_19910::nitroxoline

SMILES: c1cc2c(ccc(c2nc1)O)[N+](=O)[O-]

InChI Key: InChIKey=RJIWZDNTCBHXAL-UHFFFAOYSA-N

Data: 7 KI  8 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 64987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 1 (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 2 (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
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Cystathionine gamma-lyase (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cystathionine gamma-lyase (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cystathionine gamma-lyase (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vacuolar aminopeptidase 1 (Baker's yeast)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	607	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
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Metallo-beta lactamase [126-247,M154L] (Klebsiella pneumoniae)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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VIM-2 type metallo-beta-lactamase (Pseudomonas aeruginosa)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vacuolar aminopeptidase 1 (Baker's yeast)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	752	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
VIM-2 type metallo-beta-lactamase (Pseudomonas aeruginosa)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metallo-beta lactamase [126-247,M154L] (Klebsiella pneumoniae)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		3.95E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		3.95E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		1.54E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		1.54E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		2.72E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM64987 (SMR000059036 | MLS000069750 | cid_19910 | nitroxol...) Show SMILES Show InChI	GoogleScholar	UniChem		2.72E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair