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BDBM64989 US8486940, 192

SMILES: O=C1OC[C@H](C2CCN(CC2)c2ccccc2)N1c1ccc2[nH]cnc2c1

InChI Key: InChIKey=ZTCQMGYVXSYDJK-GNLPSFAGNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 64989   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM64989
PNG
(US8486940, 192)
Show SMILES O=C1OC[C@H](C2CCN(CC2)c2ccccc2)N1c1ccc2[nH]cnc2c1
Show InChI InChI=1/C21H22N4O2/c26-21-25(17-6-7-18-19(12-17)23-14-22-18)20(13-27-21)15-8-10-24(11-9-15)16-4-2-1-3-5-16/h1-7,12,14-15,20H,8-11,13H2,(H,22,23)/t20-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a<1.00E+4n/an/an/an/an/an/a



Probiodrug AG

US Patent


Assay Description
Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...


US Patent US8486940 (2013)


BindingDB Entry DOI: 10.7270/Q2251GSF
More data for this
Ligand-Target Pair