BDBM6504 4-Anilino-3-cyanoquinoline deriv. 7a::4-[(4-ethoxy-3,5-dimethoxyphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile

SMILES CCOc1c(OC)cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)cc1OC

InChI Key InChIKey=AJHAZHZGPDMIEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6504   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM6504(4-[(4-ethoxy-3,5-dimethoxyphenyl)amino]-6,7-dimeth...)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2005
Entry Details Article
PubMed