BDBM65441 US9533985, 231

SMILES CCOc1cc(ccc1S(=O)(=O)Nc1cc(F)c(C(=O)N[C@@H](Cc2ccc(cn2)-n2c(=O)n(C)c3cnccc3c2=O)C(O)=O)c(F)c1)-c1ncccn1

InChI Key InChIKey=KHAGTIIOCVXAPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 65441   

LigandPNGBDBM65441(US9533985, 231)
Affinity DataIC50: 10nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent