BDBM65456 19171-19-8::4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione::Actimid::CC-4047::Pomalyst::US11059801, Compound D-4::US20230271966, Compound Pomalidomide::US9694015, 6.2::pomalidomide

SMILES: Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

InChI Key: InChIKey=UVSMNLNDYGZFPF-UHFFFAOYSA-N

Data: 3 KI  17 IC50  3 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 65456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
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Protein Aster-A (Homo sapiens)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
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Protein Aster-A (Homo sapiens)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein Aiolos (Homo sapiens)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	739	n/a	n/a	n/a	n/a	n/a	n/a
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Programmed cell death 1 ligand/protein 1 (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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DNA damage-binding protein 1/Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	8.0	70
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a
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EKC/KEOPS complex subunit TP53RK (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a
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DNA damage-binding protein 1/Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
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Tumor necrosis factor (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	37
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C-C motif chemokine 4 (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	37
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C-C motif chemokine 3 (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	37
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Mediator of DNA damage checkpoint protein 1 (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	37
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Granulocyte-macrophage colony-stimulating factor (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	37
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Interleukin-1 beta (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	37
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Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (Leishmania mexicana)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	37
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Interleukin-6 (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	37
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DNA damage-binding protein 1/Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cereblon isoform 4 (Magnetospirillum gryphiswaldense)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein cereblon (Human)	BDBM65456 (pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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