BDBM65494 eIF4A3 inhibitor, 3
SMILES Clc1ccc(cc1)[C@@H]1CN(CCN1C(=O)c1ccc(Br)cc1)C(=O)c1cnn2cc(Br)ccc12
InChI Key InChIKey=WKKAVTNXNVPCCN-QHCPKHFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 65494
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+4nMAssay Description:Binding affinity to full-length human recombinant His6-tagged eIF4A3 expressed in Escherichia coli BL21(DE3) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair