BDBM65497 CC-220 (Compound 6)::US9694015, 6.4S

SMILES: c1cc2c(c(c1)OCc3ccc(cc3)CN4CCOCC4)CN(C2=O)[C@H]5CCC(=O)NC5=O

InChI Key: InChIKey=IXZOHGPZAQLIBH-UHFFFAOYSA-N

Data: 1 KI  11 IC50  2 EC50

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 65497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA damage-binding protein 1/Protein cereblon (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	7.0	n/a
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Interleukin-6 (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	37
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Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (Leishmania mexicana)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	37
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Interleukin-1 beta (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	37
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Granulocyte-macrophage colony-stimulating factor (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	37
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Mediator of DNA damage checkpoint protein 1 (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	37
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C-C motif chemokine 3 (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	37
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C-C motif chemokine 4 (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	37
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Tumor necrosis factor (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	37
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Protein cereblon (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein Aiolos (Homo sapiens)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
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Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM65497 (CC-220 (Compound 6) | US9694015, 6.4S) Show SMILES Show InChI	GoogleScholar	UniChem		4.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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