BDBM65502 2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one::8-Br-cGMP

SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)n3c4c(nc3Br)C(=O)NC(=N4)N)O)OP(=O)(O1)O

InChI Key: InChIKey=YUFCOOWNNHGGOD-UHFFFAOYSA-N

Data: 8 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 65502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform Beta of cGMP-dependent protein kinase 1 [1-351] (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	222	n/a	n/a	7.0	n/a
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Isoform Beta of cGMP-dependent protein kinase 1 [1-351,G182E] (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	765	n/a	n/a	7.0	n/a
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Isoform Beta of cGMP-dependent protein kinase 1 [1-351,G306E] (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<2	n/a	n/a	7.0	n/a
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Isoform Beta of cGMP-dependent protein kinase 1 [5-676,G306E] (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	206	n/a	n/a	7.0	n/a
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cGMP-dependent protein kinase 2 (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	58	n/a	n/a	7.0	n/a
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cGMP-dependent protein kinase 2 [41-418] (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	7.0	n/a
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cGMP-dependent protein kinase 2 [41-418,G232E] (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11	n/a	n/a	7.0	n/a
TBA									Citation and Details
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cGMP-dependent protein kinase 2 [41-418,G356E] (Human)	BDBM65502 (2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	30	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair