BDBM65505 PET-cGMP

SMILES: O[C@@H]1[C@@H]2OP(O)(=O)OC[C@H]2O[C@H]1n1cnc2c1[nH]c1nc(cn1c2=O)-c1ccccc1

InChI Key: InChIKey=TVSIKYJKUPRIDV-UHFFFAOYSA-N

Data: 8 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 65505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform Beta of cGMP-dependent protein kinase 1 [1-351] (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.80	n/a	n/a	7.0	n/a
TBA									Citation and Details
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Isoform Beta of cGMP-dependent protein kinase 1 [1-351,G182E] (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.80	n/a	n/a	7.0	n/a
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Isoform Beta of cGMP-dependent protein kinase 1 [1-351,G306E] (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<2	n/a	n/a	7.0	n/a
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Isoform Beta of cGMP-dependent protein kinase 1 [5-676,G306E] (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	18	n/a	n/a	7.0	n/a
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cGMP-dependent protein kinase 2 (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	225	n/a	n/a	7.0	n/a
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cGMP-dependent protein kinase 2 [41-418] (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	193	n/a	n/a	7.0	n/a
TBA									Citation and Details
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cGMP-dependent protein kinase 2 [41-418,G232E] (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.96E+3	n/a	n/a	7.0	n/a
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cGMP-dependent protein kinase 2 [41-418,G356E] (Human)	BDBM65505 (PET-cGMP) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.30	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair