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BDBM6570 6-(2,6-dichlorophenyl)-2-[(4-ethoxyphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD173958

SMILES: CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1

InChI Key: InChIKey=AFZKXALTXCNQAZ-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6570
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM6570 (6-(2,6-dichlorophenyl)-2-[(4-ethoxyphenyl)amino]-8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16.3	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM6570 (6-(2,6-dichlorophenyl)-2-[(4-ethoxyphenyl)amino]-8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	451	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM6570 (6-(2,6-dichlorophenyl)-2-[(4-ethoxyphenyl)amino]-8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM6570 (6-(2,6-dichlorophenyl)-2-[(4-ethoxyphenyl)amino]-8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair