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BDBM66003 (5E)-1-(4-fluorobenzyl)-5-(2-thenylidene)barbituric acid::(5E)-1-[(4-fluorophenyl)methyl]-5-(thiophen-2-ylmethylidene)-1,3-diazinane-2,4,6-trione::1-(4-Fluoro-benzyl)-5-[1-thiophen-2-yl-meth-(E)-ylidene]-pyrimidine-2,4,6-trione::MLS000592022::SMR000218269::cid_5418979

SMILES: Fc1ccc(CN2C(=O)NC(=O)\C(=C/c3cccs3)C2=O)cc1

InChI Key: InChIKey=GYIGZACWAPWURC-MDWZMJQESA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 66003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RPL19A


(Saccharomyces cerevisiae)
BDBM66003
PNG
((5E)-1-(4-fluorobenzyl)-5-(2-thenylidene)barbituri...)
Show SMILES Fc1ccc(CN2C(=O)NC(=O)\C(=C/c3cccs3)C2=O)cc1
Show InChI InChI=1S/C16H11FN2O3S/c17-11-5-3-10(4-6-11)9-19-15(21)13(14(20)18-16(19)22)8-12-2-1-7-23-12/h1-8H,9H2,(H,18,20,22)/b13-8+
PDB
MMDB

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KEGG

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PCBioAssay
n/an/an/an/a 4.65E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2JQ0ZGP
More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM66003
PNG
((5E)-1-(4-fluorobenzyl)-5-(2-thenylidene)barbituri...)
Show SMILES Fc1ccc(CN2C(=O)NC(=O)\C(=C/c3cccs3)C2=O)cc1
Show InChI InChI=1S/C16H11FN2O3S/c17-11-5-3-10(4-6-11)9-19-15(21)13(14(20)18-16(19)22)8-12-2-1-7-23-12/h1-8H,9H2,(H,18,20,22)/b13-8+
PDB

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antibodypedia
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n/an/an/an/a 1.26E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q22N50RJ
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM66003
PNG
((5E)-1-(4-fluorobenzyl)-5-(2-thenylidene)barbituri...)
Show SMILES Fc1ccc(CN2C(=O)NC(=O)\C(=C/c3cccs3)C2=O)cc1
Show InChI InChI=1S/C16H11FN2O3S/c17-11-5-3-10(4-6-11)9-19-15(21)13(14(20)18-16(19)22)8-12-2-1-7-23-12/h1-8H,9H2,(H,18,20,22)/b13-8+
PDB

KEGG

UniProtKB/SwissProt

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PC cid
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UniChem

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n/an/an/an/a 3.41E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair
MEP2


(Saccharomyces cerevisiae)
BDBM66003
PNG
((5E)-1-(4-fluorobenzyl)-5-(2-thenylidene)barbituri...)
Show SMILES Fc1ccc(CN2C(=O)NC(=O)\C(=C/c3cccs3)C2=O)cc1
Show InChI InChI=1S/C16H11FN2O3S/c17-11-5-3-10(4-6-11)9-19-15(21)13(14(20)18-16(19)22)8-12-2-1-7-23-12/h1-8H,9H2,(H,18,20,22)/b13-8+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 3.01E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2F18X5F
More data for this
Ligand-Target Pair