BDBM66286 2,6-bis(azanyl)-4-(2,5-dimethylthiophen-3-yl)-4H-thiopyran-3,5-dicarbonitrile::2,6-diamino-4-(2,5-dimethyl-3-thienyl)-4H-thiopyran-3,5-dicarbonitrile::2,6-diamino-4-(2,5-dimethyl-3-thiophenyl)-4H-thiopyran-3,5-dicarbonitrile::2,6-diamino-4-(2,5-dimethylthiophen-3-yl)-4H-thiopyran-3,5-dicarbonitrile::MLS000049335::SMR000075217::cid_2172625

SMILES Cc1cc(C2C(C#N)C(=N)SC(=N)C2C#N)c(C)s1

InChI Key InChIKey=TWGYBULSNGOWMM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 66286   

TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66286(SMR000075217 | cid_2172625 | 2,6-diamino-4-(2,5-di...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66286(SMR000075217 | cid_2172625 | 2,6-diamino-4-(2,5-di...)
Affinity DataEC50: >5.00E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay