BDBM6644 6‐phenylpteridine‐2,4,7‐triamine (5)::6-phenylpteridine-2,4,7-triamine::Pteridine deriv. 11::TRIAMTERENE

SMILES: Nc1nc(N)c2nc(c(N)nc2n1)-c1ccccc1

InChI Key: InChIKey=FNYLWPVRPXGIIP-UHFFFAOYSA-N

Data: 1 KI  11 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 6644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C] (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	7.4	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
dTDP-4-dehydrorhamnose 3,5-epimerase (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock factor protein 1 (Mouse)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.95E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Casein kinase I isoform alpha (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.64E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylalanine-4-hydroxylase (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM6644 (Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair