BDBM6655 3-(9-oxo-9H-fluoren-4-yl)-1-pyridin-2-ylurea::Diarylurea deriv. 15::N-(9-Oxo-9H-fluoren-4-yl)-N -pyridin-2-ylurea
SMILES O=C(Nc1ccccn1)Nc1cccc2C(=O)c3ccccc3-c12
InChI Key InChIKey=XVVDNGPUSVDRAJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 6655
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D2(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant CDK4/Cyclin D2 expressed in baculovirus infected insect Sf9 cells using G1 peptide as substrate after 45 mins by Top ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Banyu Tsukuba Research Institute
Banyu Tsukuba Research Institute
Affinity DataIC50: 100nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair