BDBM66574 (5E)-1,1-diketo-2-(3-nitrophenyl)-3-p-phenetyl-5-vanillylidene-1,3-thiazolidin-4-one::(5E)-3-(4-ethoxyphenyl)-5-(4-hydroxy-3-methoxybenzylidene)-2-(3-nitrophenyl)-1,3-thiazolidin-4-one 1,1-dioxide::(5E)-3-(4-ethoxyphenyl)-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-2-(3-nitrophenyl)-1,1-bis(oxidanylidene)-1,3-thiazolidin-4-one::(5E)-3-(4-ethoxyphenyl)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(3-nitrophenyl)-1,1-dioxo-1,3-thiazolidin-4-one::MLS000682290::SMR000314651::cid_16193931

SMILES CCOc1ccc(cc1)N1C(c2cccc(c2)[N+]([O-])=O)S(=O)(=O)\C(=C\c2ccc(O)c(OC)c2)C1=O

InChI Key InChIKey=FJLJOQIRHXPRGE-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 66574   

TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM66574((5E)-3-(4-ethoxyphenyl)-5-(4-hydroxy-3-methoxybenz...)
Affinity DataIC50: 1.89E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM66574((5E)-3-(4-ethoxyphenyl)-5-(4-hydroxy-3-methoxybenz...)
Affinity DataIC50: 1.89E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66574((5E)-3-(4-ethoxyphenyl)-5-(4-hydroxy-3-methoxybenz...)
Affinity DataEC50:  8.52E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM66574((5E)-3-(4-ethoxyphenyl)-5-(4-hydroxy-3-methoxybenz...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetProbable nicotinate-nucleotide adenylyltransferase(Staphylococcus aureus subsp. aureus N315)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM66574((5E)-3-(4-ethoxyphenyl)-5-(4-hydroxy-3-methoxybenz...)
Affinity DataIC50: 3.59E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66574((5E)-3-(4-ethoxyphenyl)-5-(4-hydroxy-3-methoxybenz...)
Affinity DataEC50:  5.66E+4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay