BDBM66640 (4E)-1-(2-furanylmethyl)-4-[hydroxy-(3-nitrophenyl)methylidene]-5-thiophen-2-ylpyrrolidine-2,3-dione::(4E)-1-(2-furfuryl)-4-[hydroxy-(3-nitrophenyl)methylene]-5-(2-thienyl)pyrrolidine-2,3-quinone::(4E)-1-(furan-2-ylmethyl)-4-[(3-nitrophenyl)-oxidanyl-methylidene]-5-thiophen-2-yl-pyrrolidine-2,3-dione::(4E)-1-(furan-2-ylmethyl)-4-[hydroxy-(3-nitrophenyl)methylidene]-5-thiophen-2-ylpyrrolidine-2,3-dione::1-Furan-2-ylmethyl-3-hydroxy-4-(3-nitro-benzoyl)-5-thiophen-2-yl-1,5-dihydro-pyrrol-2-one::MLS000769730::SMR000434521::cid_5916371

SMILES [O-][N+](=O)c1cccc(c1)C(=O)C1C(N(Cc2ccco2)C(=O)C1=O)c1cccs1

InChI Key InChIKey=ZRMNIEZDAHTATG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 66640   

TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66640(SMR000434521 | 1-Furan-2-ylmethyl-3-hydroxy-4-(3-n...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay