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BDBM66773 2-[2-[(Z)-(5-bromanyl-2-oxidanylidene-1H-indol-3-ylidene)methyl]phenoxy]ethanoic acid::2-[2-[(Z)-(5-bromo-2-keto-indolin-3-ylidene)methyl]phenoxy]acetic acid::2-[2-[(Z)-(5-bromo-2-oxo-1H-indol-3-ylidene)methyl]phenoxy]acetic acid::MLS001196427::SMR000556282::cid_1020488::{2-[(Z)-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]phenoxy}acetic acid

SMILES: OC(=O)COc1ccccc1\C=C1/C(=O)Nc2ccc(Br)cc12

InChI Key: InChIKey=XNYJPURGJHFBQX-QPEQYQDCSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 66773   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bcl-2-like protein 11


(Homo sapiens (Human))
BDBM66773
PNG
(2-[2-[(Z)-(5-bromanyl-2-oxidanylidene-1H-indol-3-y...)
Show SMILES OC(=O)COc1ccccc1\C=C1/C(=O)Nc2ccc(Br)cc12
Show InChI InChI=1S/C17H12BrNO4/c18-11-5-6-14-12(8-11)13(17(22)19-14)7-10-3-1-2-4-15(10)23-9-16(20)21/h1-8H,9H2,(H,19,22)(H,20,21)/b13-7-
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PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair