BDBM66976 (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;hydrate::(1S,3R)-1-azanylcyclopentane-1,3-dicarboxylic acid;hydrate::CHEMBL34453::MLS002153209::SMR001230688::cid_16218853::trans-( )-ACPD monohydrate

SMILES: C1C[C@](C[C@@H]1C(=O)O)(C(=O)O)N

InChI Key: InChIKey=YFYNOWXBIBKGHB-UHFFFAOYSA-N

Data: 7 KI  39 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 46 hits for monomerid = 66976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Metabotropic glutamate receptor 1 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a
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Bcl-2-like protein 11 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.50E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Metabotropic glutamate receptor 8 (Mouse)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
TBA									Citation and Details
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Human)	BDBM66976 (SMR001230688 | trans-( )-ACPD monohydrate | cid_16...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair