BDBM673161 (1r,4r)-4-(3-chloroanilino)-2′-(2,3-dihydro-1-benzofuran-7-yl)-2′,3′-dihydrospiro[cyclohexane-1,1′-indene]-4-carboxylic acid, enantiomer 2::US20240150293, Example 296

SMILES OC(=O)[C@H]1CC[C@@]2(CC1Nc1cccc(Cl)c1)C(Cc1ccccc21)c1cccc2CCOc12

InChI Key InChIKey=BLUZFCGNZCXLAX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673161   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673161(US20240150293, Example 296 | (1r,4r)-4-(3-chloroan...)
Affinity DataKi:  3.46E+3nMAssay Description:The relative binding potency of each compound was determined via Fluorescence Polarisation (FP). The method utilised a Fluorescein labelled ligand (F...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent