BDBM673178 (1s,4s)-4-(3-chloroanilino)-2′-(3-ethoxyphenyl)spiro[cyclohexane-1,1′-indene]-4-carboxylic acid::US20240150293, Example 313

SMILES CCOc1cccc(c1)C1=Cc2ccccc2[C@@]11CC[C@](CC1)(Nc1cccc(Cl)c1)C(O)=O

InChI Key InChIKey=JNRMTWXSUTYNMM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673178   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673178(US20240150293, Example 313 | (1s,4s)-4-(3-chloroan...)
Affinity DataKi:  385nMAssay Description:The relative binding potency of each compound was determined via Fluorescence Polarisation (FP). The method utilised a Fluorescein labelled ligand (F...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent