BDBM673179 (1s,4s)-4-(3-chloroanilino)-2′-[3-(trifluoromethoxy)phenyl]spiro[cyclohexane-1,1′-indene]-4-carboxylic acid::US20240150293, Example 314

SMILES OC(=O)[C@]1(CC[C@@]2(CC1)C(=Cc1ccccc21)c1cccc(OC(F)(F)F)c1)Nc1cccc(Cl)c1

InChI Key InChIKey=SHGLRILKVRQBDR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673179   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673179(US20240150293, Example 314 | (1s,4s)-4-(3-chloroan...)
Affinity DataKi:  528nMAssay Description:The relative binding potency of each compound was determined via Fluorescence Polarisation (FP). The method utilised a Fluorescein labelled ligand (F...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent