BDBM67544 N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazinyl]-1-propanamine;hydrochloride::N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine;hydrochloride::SR-01000000224-4::TRIFLUPROMAZINE::cid_66069::dimethyl-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]amine;hydrochloride::med.21724, Compound Triflupromazine

SMILES: CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F

InChI Key: InChIKey=XSCGXQMFQXDFCW-UHFFFAOYSA-N

Data: 9 KI  5 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 67544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 1 (Human)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Pleiotropic ABC efflux transporter of multiple drugs (Baker's yeast)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.39E+3	n/a	n/a	n/a	n/a
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Orf1a protein (MERS-CoV)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a
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Proteasome subunit alpha type-6 (Human)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.80E+3	n/a	n/a	7.5	37
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D(2) dopamine receptor (Bovine)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Rat)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Bovine)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Bovine)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Guinea pig)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		605	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Trypanothione reductase (Trypanosoma cruzi)	BDBM67544 (TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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