BDBM67545 N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine;hydrochloride::N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride::PROMAZINE::SR-01000000228-4::US9504692, Promazine::cid_5887::dimethyl(3-phenothiazin-10-ylpropyl)amine;hydrochloride

SMILES: CN(C)CCCN1c2ccccc2Sc3c1cccc3

InChI Key: InChIKey=ZGUGWUXLJSTTMA-UHFFFAOYSA-N

Data: 21 KI  10 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 67545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 1/2/3 subunit alpha (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A)/D(2) dopamine receptor (Bovine)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Rat)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Pleiotropic ABC efflux transporter of multiple drugs (Baker's yeast)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Major prion protein (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	30
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NADPH oxidase 1 (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histamine H1 receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		5.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		15.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Rat)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		71.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		159	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		909	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(1A) dopamine receptor (Bovine)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Bovine)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 1A/1B/1D/2C (Human)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Trypanothione reductase (Trypanosoma cruzi)	BDBM67545 (cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...) Show SMILES Show InChI	GoogleScholar	UniChem		5.91E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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