BDBM6756 1,7-Annulated indolocarbazole deriv. 16-b::7-fluoro-24-[(methylamino)methyl]-1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0^{5,10}.0^{12,16}.0^{22,26}]hexacosa-2(17),3(11),5(10),6,8,12(16),18(26),19,21-nonaene-13,15-dione hydrochloride

SMILES CNCC1Cc2cccc3c4c5C(=O)NC(=O)c5c5c6ccc(F)cc6[nH]c5c4n(C1)c23

InChI Key InChIKey=URRKLWBDEXHZPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6756   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Eli Lilly

LigandPNGBDBM6756(1,7-Annulated indolocarbazole deriv. 16-b | 7-fluo...)
Affinity DataIC50:  383nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM6756(1,7-Annulated indolocarbazole deriv. 16-b | 7-fluo...)
Affinity DataIC50:  8nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed