BDBM6780 3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::bis-indolylmaleimide deriv. 8j

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cn(CC(O)CO)c3ccccc23)c2ccccc12

InChI Key: InChIKey=UBUCTCIBRLMJKZ-UHFFFAOYSA-N

Data: 4 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM6780 (3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	7.0	22
TBA									Citation and Details
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM6780 (3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM6780 (3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM6780 (3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair