BDBM680386 2-Difluoromethoxy-4-{6-[2-(7-fluoro-2,4-dimethyl-indol-1-yl)-ethylamino]-pyrimidin-4- yl}-benzoic acid::US12011444, Example 601

SMILES Cc1cc2c(C)ccc(F)c2n1CCNc1cc(ncn1)-c1ccc(C(O)=O)c(OC(F)F)c1

InChI Key InChIKey=ZZCUFHCJOPCUSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680386   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680386(US12011444, Example 601 | 2-Difluoromethoxy-4-{6-[...)
Affinity DataIC50: 12nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680386(US12011444, Example 601 | 2-Difluoromethoxy-4-{6-[...)
Affinity DataIC50: 122nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent