BDBM680421 4-{6-[2-(6,7-Difluoro-4-methoxy-2-methyl-indol-1-yl)-ethylamino]-pyrimidin-4-yl}-2- trifluoromethoxy-benzoic acid::US12011444, Example 636

SMILES COc1cc(F)c(F)c2n(CCNc3cc(ncn3)-c3ccc(C(O)=O)c(OC(F)(F)F)c3)c(C)cc12

InChI Key InChIKey=FDRVYDOCYJVRIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680421   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680421(US12011444, Example 636 | 4-{6-[2-(6,7-Difluoro-4-...)
Affinity DataIC50: 68nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680421(US12011444, Example 636 | 4-{6-[2-(6,7-Difluoro-4-...)
Affinity DataIC50: 255nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent