BDBM680469 US12011444, Example 684::[2-(7-Chloro-4-methoxy-2-methyl-indol-1-yl)-ethyl]-{6-[3-methoxy-4-(1H-tetrazol-5-yl)- phenyl]-pyrimidin-4-yl}-amine

SMILES COc1cc(ccc1-c1nnn[nH]1)-c1cc(NCCn2c(C)cc3c(OC)ccc(Cl)c23)ncn1

InChI Key InChIKey=JXXDFXVQLNVKQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680469   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680469(US12011444, Example 684 | [2-(7-Chloro-4-methoxy-2...)
Affinity DataIC50: 36nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680469(US12011444, Example 684 | [2-(7-Chloro-4-methoxy-2...)
Affinity DataIC50: 471nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent