BDBM68249 Microlactone, 16a

SMILES Oc1cc(O)c2c(CC(=O)CCCC[C@H]3O[C@@H]3CCOC2=O)c1Cl

InChI Key InChIKey=ARHWBYVAVSJMRF-ZIAGYGMSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 68249   

TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68249(Microlactone, 16a)
Affinity DataIC50:  2.10E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68249(Microlactone, 16a)
Affinity DataIC50:  310nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68249(Microlactone, 16a)
Affinity DataIC50:  190nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68249(Microlactone, 16a)
Affinity DataIC50:  2.50E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed