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BDBM68349 4-[(4-Benzothiazol-2-yl-piperazin-1-yl)-(1-tert-butyl-1H-tetrazol-5-yl)-methyl]-2-methoxy-phenol::4-[[4-(1,3-benzothiazol-2-yl)-1-piperazinyl]-(1-tert-butyl-5-tetrazolyl)methyl]-2-methoxyphenol::4-[[4-(1,3-benzothiazol-2-yl)piperazin-1-yl]-(1-tert-butyl-1,2,3,4-tetrazol-5-yl)methyl]-2-methoxy-phenol::4-[[4-(1,3-benzothiazol-2-yl)piperazin-1-yl]-(1-tert-butyltetrazol-5-yl)methyl]-2-methoxyphenol::4-[[4-(1,3-benzothiazol-2-yl)piperazino]-(1-tert-butyltetrazol-5-yl)methyl]-2-methoxy-phenol::MLS000027473::SMR000004488::cid_646829

SMILES: COc1cc(ccc1O)C(N1CCN(CC1)c1nc2ccccc2s1)c1nnnn1C(C)(C)C

InChI Key: InChIKey=YXRSVQGMZRIIJG-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 68349   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM68349
PNG
(4-[(4-Benzothiazol-2-yl-piperazin-1-yl)-(1-tert-bu...)
Show SMILES COc1cc(ccc1O)C(N1CCN(CC1)c1nc2ccccc2s1)c1nnnn1C(C)(C)C
Show InChI InChI=1S/C24H29N7O2S/c1-24(2,3)31-22(26-27-28-31)21(16-9-10-18(32)19(15-16)33-4)29-11-13-30(14-12-29)23-25-17-7-5-6-8-20(17)34-23/h5-10,15,21,32H,11-14H2,1-4H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair