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BDBM68535 MLS000049659::N-[2-(3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]-N,4-dimethylbenzenesulfonamide (non-preferred name)::N-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-keto-ethyl]-N,4-dimethyl-benzenesulfonamide::N-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxidanylidene-ethyl]-N,4-dimethyl-benzenesulfonamide::N-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]-N,4-dimethylbenzenesulfonamide::SMR000076264::cid_2203342

SMILES: CN(CC(=O)N1CCCc2ccccc12)S(=O)(=O)c1ccc(C)cc1

InChI Key: InChIKey=ZXKWKSANWWOYEF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 68535   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Axin-1/Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM68535
PNG
(MLS000049659 | N-[2-(3,4-dihydro-1(2H)-quinolinyl)...)
Show SMILES CN(CC(=O)N1CCCc2ccccc12)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C19H22N2O3S/c1-15-9-11-17(12-10-15)25(23,24)20(2)14-19(22)21-13-5-7-16-6-3-4-8-18(16)21/h3-4,6,8-12H,5,7,13-14H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair