BDBM685744 (R)-N-allyl-N-(1-(4-methoxyphenyl)ethyl)- 3,3-diphenylprop-2-en-1-amine::US12043602, Compound NY0217

SMILES [#6]-[#6@@H](-[#7](-[#6]-[#6]=[#6])-[#6]\[#6]=[#6](\c1ccccc1)-c1ccccc1)-c1ccc(-[#8])cc1

InChI Key InChIKey=QADZXCKECBCLTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685744   

TargetGTPase KRas [G12V](Human)
University of Texas

US Patent
LigandPNGBDBM685744(US12043602, Compound NY0217 | (R)-N-allyl-N-(1-(4-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Table 1: Potency and efficacy of K-RAS inhibition and toxicity of batch1 and 2 compounds. MDCK cells co-expressing GFP-K-RASG12V and mCherry-CAAX wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
US Patent