BDBM68676 2-[2-(5-Isopropyl-4-methyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetylamino]-4-methyl-thiazole-5-carboxylic acid ethyl ester::2-[[2-[(5-isopropyl-4-methyl-1,2,4-triazol-3-yl)thio]acetyl]amino]-4-methyl-thiazole-5-carboxylic acid ethyl ester::4-methyl-2-[[2-[(4-methyl-5-propan-2-yl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]amino]-5-thiazolecarboxylic acid ethyl ester::MLS000121693::SMR000119043::cid_3212566::ethyl 4-methyl-2-[2-[(4-methyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethanoylamino]-1,3-thiazole-5-carboxylate::ethyl 4-methyl-2-[[2-[(4-methyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]-1,3-thiazole-5-carboxylate

SMILES CCOC(=O)c1sc(NC(=O)CSc2nnc(C(C)C)n2C)nc1C

InChI Key InChIKey=BEYHJEIISVYDLS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 68676   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM68676(2-[2-(5-Isopropyl-4-methyl-4H-[1,2,4]triazol-3-yls...)
Affinity DataEC50:  2.60E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay