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BDBM68723 MLS000552435::N-(3,5-Dichloro-phenyl)-2-(3-oxo-piperazin-2-yl)-acetamide::N-(3,5-dichlorophenyl)-2-(3-ketopiperazin-2-yl)acetamide::N-(3,5-dichlorophenyl)-2-(3-oxo-2-piperazinyl)acetamide::N-(3,5-dichlorophenyl)-2-(3-oxopiperazin-2-yl)acetamide::N-[3,5-bis(chloranyl)phenyl]-2-(3-oxidanylidenepiperazin-2-yl)ethanamide::SMR000145950::cid_4011635

SMILES: Clc1cc(Cl)cc(NC(=O)CC2NCCNC2=O)c1

InChI Key: InChIKey=FIBIBAITWGRILM-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 68723   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM68723
PNG
(MLS000552435 | N-(3,5-Dichloro-phenyl)-2-(3-oxo-pi...)
Show SMILES Clc1cc(Cl)cc(NC(=O)CC2NCCNC2=O)c1
Show InChI InChI=1S/C12H13Cl2N3O2/c13-7-3-8(14)5-9(4-7)17-11(18)6-10-12(19)16-2-1-15-10/h3-5,10,15H,1-2,6H2,(H,16,19)(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair