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BDBM69225 2-chloroethyl N-[1-(1H-indol-3-yl)propan-2-yl]carbamate::MLS000710036::N-[1-(1H-indol-3-yl)propan-2-yl]carbamic acid 2-chloroethyl ester::N-[2-(1H-indol-3-yl)-1-methyl-ethyl]carbamic acid 2-chloroethyl ester::SMR000287203::cid_2827474

SMILES: CC(Cc1c[nH]c2ccccc12)NC(=O)OCCCl

InChI Key: InChIKey=YXUIWPHGOSIKIF-UHFFFAOYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 69225   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM69225
PNG
(2-chloroethyl N-[1-(1H-indol-3-yl)propan-2-yl]carb...)
Show SMILES CC(Cc1c[nH]c2ccccc12)NC(=O)OCCCl
Show InChI InChI=1/C14H17ClN2O2/c1-10(17-14(18)19-7-6-15)8-11-9-16-13-5-3-2-4-12(11)13/h2-5,9-10,16H,6-8H2,1H3,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair