BDBM69277 4-(4-methyl-1-piperazinyl)-2,6-diphenyl-5-pyrimidinecarbonitrile::4-(4-methylpiperazin-1-yl)-2,6-diphenyl-pyrimidine-5-carbonitrile::4-(4-methylpiperazin-1-yl)-2,6-diphenylpyrimidine-5-carbonitrile::4-(4-methylpiperazino)-2,6-diphenyl-5-pyrimidinecarbonitrile::4-(4-methylpiperazino)-2,6-diphenyl-pyrimidine-5-carbonitrile::MLS000694520::SMR000333197::cid_1480493

SMILES CN1CCN(CC1)c1nc(nc(-c2ccccc2)c1C#N)-c1ccccc1

InChI Key InChIKey=PVSSXSWACOFACA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 69277   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69277(4-(4-methylpiperazin-1-yl)-2,6-diphenyl-pyrimidine...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay