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BDBM69328 2-(4,4-diethyl-2,5-diketo-imidazolidin-1-yl)acetic acid [2-[(3-cyano-2-thienyl)amino]-2-keto-ethyl] ester::2-(4,4-diethyl-2,5-dioxo-1-imidazolidinyl)acetic acid [2-[(3-cyano-2-thiophenyl)amino]-2-oxoethyl] ester::MLS001017506::SMR000353773::[2-[(3-cyanothiophen-2-yl)amino]-2-oxidanylidene-ethyl] 2-[4,4-diethyl-2,5-bis(oxidanylidene)imidazolidin-1-yl]ethanoate::[2-[(3-cyanothiophen-2-yl)amino]-2-oxoethyl] 2-(4,4-diethyl-2,5-dioxoimidazolidin-1-yl)acetate::cid_2551904

SMILES: CCC1(CC)NC(=O)N(CC(=O)OCC(=O)Nc2sccc2C#N)C1=O

InChI Key: InChIKey=OKJKGDJPPVHCQA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 69328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM69328
PNG
(2-(4,4-diethyl-2,5-diketo-imidazolidin-1-yl)acetic...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)OCC(=O)Nc2sccc2C#N)C1=O
Show InChI InChI=1S/C16H18N4O5S/c1-3-16(4-2)14(23)20(15(24)19-16)8-12(22)25-9-11(21)18-13-10(7-17)5-6-26-13/h5-6H,3-4,8-9H2,1-2H3,(H,18,21)(H,19,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair